He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. Snores like a big dog. Our pups had been on next guard and heart guard with no issues but new vet stopped selling those products so switched to to the simparica trio - gave a dose to our 7 ur old 71 pound blue tick coonhound Frazier and our 10 mo 45 pound labradoodle- Watson. Our golden retriever had his first seizure after taking Simparica Trio last October. He walked outside peed then tried to come back in the house but his legs gave out . Im not sure if the simperica is the cause. It may be that he is getting older as he is now one years old and he was neutered about three months ago. I cant believe how long this thread is. No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. She is lethargic and doesnt want to eat. Today really soft stool (not diarrhea but close). Use a collar or topical if you need to. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. By Sunday he is having liquid diarrhea! Gave Simparica to my dog yesterday. Although much improved, she continues to exhibit left side bias, with frequent left circling. They are both potty trained, but one keeps using the bathroom in the house. The most common Simparica Trio for dogs side effects are; Lethargy Vomiting Diarrhea Loss of appetite Polydipsia Polyuria Hyperactivity Hyperactivity, polydipsia, and polyuria happened in very rare cases. My Pomeranian is on a steady decline after taking 1 dose. Then on day 5 my poor dog just couldnt move. We are doing one more increase and if that doesnt help, we will be adding zonisamide. I started using this for my 5 year old black lab in October 2020, So she had 2 doses and in December she became very sick vomiting and would hardly eat and had a hard time walking up the stepsTook her to the vet and she couldn't find anything wrong with her. I would NEVER recommend this medication. These products are approved for the treatment and prevention of flea infestations, and the treatment and control of tick infestations. best of luck to all whose furry ones have gotten sick from this and as well hugs to those who lost their beloved pets. The most common side effects of Simparica in dogs are vomiting and diarrhea. The day after administering drug he had two incapacitating seizures. Shes not the carefree setter she was prior to this medication. I put him on boiled chicken & rice and got him calmed down. My precious rescue has been sick twice, currently on her second episode. Had I of done my research before hand, I never would have giving it to him in the first place. This is so scary. I have every intention of calling and filing a complaint. Is your dog still having tremors? She has NEVER done that before. He has never acted like he was in pain. Then a week later 2 more just 24 hours apart then a little over w week later she had 3 in 24 hours. This behavior is so inconsistent and confusing. It's definitely not! But he still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non stop. I have a chihuahua/miniature pincher mix dog thats 9 yrs. All antiparasitics for dogs lower the seizure threshold. Gave our Bloodhound Simparico Trip on Tuesday on Thursday he got extremely thirsty and was peeing everywhere from drinking so much water. Our dog has had 2 Seizures this month and we are going to stop using Simparica. Reported this to FDA today-, My 14 year old was up on simparica about a year ago and her whole demeanor has changed. It's only available with a prescription from your veterinarian, so you cannot get it over-the-counter. Very small sample - many deformities, stillborn. My 8 month old labradoodle has had 2 doses of Simparico Trio. This is terrible. They gave him a strong shot of prednisone that was good for 2 days . Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a history of seizures. Vet says garlic doesn't work and obviously it didn't because he shaved a little of dogs fur and put it on a paper towels and it was full of fleas.The vet gives me Simpirica-ok fleas are dropping off him like crazy. Mammals also have GABA receptors in the brain and I've been reading on other websites about both nervous and aggressive behaviors in normally docile pets in the days following ingestion of Simparica Trio occurring and astute pet owners begin wondering if there is a connection. We administered the first dose on Wednesday June 1st to our 9 year old bouvier flanders. The next day, we took him to his vet and had several tests ran (x-rays, bloodwork, etc.). He has been resting most of the day so far, thankfully no seizures.. but I promise I will not be giving him the other 2 doses I got from the vet after reading all of the experiences everyone else has had with their animals. Not to worry you, and I hope yours is different outcome! Use with caution in dogs with a history of seizures or neurologic disorders. She would constantly twirl in left circles. Next day, he was suddenly 1000% worse, would not touch food, could not move. He is not the same puppy prior to two days ago! I have another dog, but gave him Frontline and he's fine. But I noticed that I had to "wake him' several times in only 2 minutes time, but he wasn't sleeping, his eyes were open and I saw them rolling in the back of his head! My other Lab after 5 days started having severe diaherria (black at first, now golden) and now throwing up too. Which Type of Dog Fence Is Right For Your Pet? He is my first dog, he is 5yrs old now, and this is all new. This is terrible. He is fully housebroken and just had a running stool accident in the house. I hope I have found the culprit to his digression. He collapsed & went limp in my arms . Mine has tremors once in a while and now I know why! We did not make the connection until today. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. They said , he has a Autoimmune Hemolytic anemia . He was a Shih Tzu. He had to be put to sleep and Im devastated. Glad i held off on the free sample i was given! (which I already had read about and did not want to give this prescription to my dog), but so the two nurses at the front desk of my vet continued to say that they prefer simparica. Only some dogs show this symptom. Speak with your veterinarian about what to do if you forget to give a dose of Simparica or Simparica Trio. He never ever used to do this. My sincere sympathies to those with horrendous seizure side effects. Took her to her Vet where I was told she had another tremor. The American Heartworm Society recommends year-round heartworm prevention for all dogs in the United States, and the Companion Animal Parasite Council recommends broad-spectrum parasite control to prevent heartworms, intestinal parasites, fleas, and ticks for all dogs in North America. I have ordered what I normally use and will throw this in the trash! She couldnt walk straight anymore and stopped eating. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). Now that Ive read all these comments I think he has developed these issues because of this trio medication. Eyes roll back. she has shaking off and on . On 08/06 she threw up. My dog just had 1 and he already has seizure medication - the vet reckons it was the best 1 to help not get the seizures. Update:(12/20/21) my dog has now been able to go up and down steps with no hesitation. Today is Friday. Will be talking to the vet inregards to his side effects. Nexgard can cause lethargy and a loss of appetite in dogs. Are there any side effects to Simparica Trio? I gave this to my 2 rescue frenchies.. 2 days after 1 of them threw up..she didn't want to eat and started stumbling..leaning to the right, I thought vestibular but that is old dogs disease..I took her to the vet, did bloodwork that came back ok..she is on steroids and anti nausea meds..she is eating now..drinking alot and acts like she is deaf..she is only 6 yrs old. No vet writer or qualified reviewer has received any compensation from the manufacturer of the medication as part of creating this article. Saturday he started up the drinking again and threw up his breakfast. I could never forgive myself. How long did the itchiness last for your schnauzer? What Are Potential Simparica Trio Side Effects in Dogs? My dog (6 years old) has been using monthly Simparica since I got him. I am starting to get scared they are both 80 lbs and the other dog is. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. It started working on him right away, Diarrhea. Over two weeks later she still can not walk properly. My personal dog has had no issues at all, and she's been on it for nearly two years. My family saw it , I did not . Gave my 12 year old labradoodle simpatico just before going to my sons for T-Day dinner. Then suddenly dog has diarrhea and it lasted for several days. Its crazy to think they dont recover and can die in a few months. She had multiple seizures and developed pericardial effusion and myocarditis. His skin became itchy and his eyes were too. I dont know what to do to get this out of their system?? Our dog had her first dose June 1st 2022 - diarrhea, scratching, excessive thirst. He is 11 so I attributed his slowing down on walks to aging but now he is recently limping and at times has some trouble with jumping up on the bed. My 3 year old dog has been on Simparica since he was a puppy, with no side effects that I've noticed. 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. What You Need to Know About the Lyme Vaccine for Dogs. This sounds so scary. She definitely is not herself and behaving strangely. This is because it doesn't kill adult heartworms. What is Simparica Trio for dogs? Never saw tremors before. I will keep a close eye on him and hopefully nothing else come about, we will NEVER take this medication again! Like other oral treatments, Simparicaworks by entering a dogs bloodstream immediately after ingestion. He just couldn't stand good, he constantly shakes his head. We started the medication on Dec. 1st and 3 days later it started with vomiting and loss of appetite. In a well-controlled laboratory study, SIMPARICA TRIO began to kill fleas at 4 hours and demonstrated 100% effectiveness at 8 hours after initial administration. I will never give my dog this medication again. In a weak moment last week she prescribed Simparica for a flea problem my 5 year old Springer was having. A couple of weeks later she had lost weight from not eating. She will not get this anymore. I went to zoetis and Expressed my views and they said the FDA report meant nothing and it was in America. Plus I spent a fortune for the crap We gave our Pomeranian the first dose of simpatica on 4/30 - yesterday (5/11) she had a seizure and just had another one tonight. And since then has had diarrhea and loose poop. The vet does not feel it is due to Simparica but i think it could be. There is a possibility it isn't the cause, but it is the only reason I can find and it aligns with the stories of others. Simparica Trio is safe to give in conjunction with most other medications, but be sure to tell your vet about all medications and supplements you give to your dog. How is your puppy doing? After being ingested by a dog, sarolaner is distributed throughout the body. Within a week one of our beloved doggies began experiencing several of the symptoms reported in this blog by other owners. We will have blood work and results this evening. This was January 15 of 2020. Not even going to risk it . She is only 6 and was so full of life and energy. This medicine needs to be stopped. My guess is their are counting on getting the dosage exactly right where it greatly affects small creature but not enough to affect big animals, however too many variables can affect the absorption in your pet's digestive tract leading to these horrible experiences being related in all the comments here. When he lays in the sun you can see the bumps under his skin. I disagree. My vet never mentioned that puppies under 6months cannot be prescribed this medication. For those who lost their dear companions from this medicine my heart goes out to you all. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. I gave my dog simparica trio. The reaction lasted less than 12 hours. And urinating more often as a result. My Miles is having this SAME issues, started Simparico Trio in May and he got his second does June 1, by June 5th he wont eat, walk and or bark! Has anyone's dog broke out with a rash on the belly, I have a miniature schnauzer at her last check up the doctor gave us the simpatico because he no longer sold the topical one I have used for years. We are now at about 45 days since last simparica and he is back to his old self. I'm just so angry that the vet prescribed this and I am mad at myself for not researching it. No problem eating. . Tasty, liver-flavored chewable tablet is easy to administer. My Havanese started having frequent lip licking and teeth clashing and swallowing after switching from Simparica to Simparica Trio. The flavored, chewable tablets were consumed . My dog is on a "health care plan" with my vet. Other signs may include: Contact your veterinarian if you notice these or other signs of illness after giving Simparica Trio to your dog. I had to put him on ani seizures meds due to some being clusters so unable to tell if he is getting better or the meds are just preventing it. Simparica is approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age. One more increase and if that doesnt help, we will have work... Stand good, he is not the same puppy prior to two days ago said FDA... This article a loss of appetite in dogs receiving isoxazoline class drugs, even in dogs everywhere drinking. Using Simparica he was neutered about three months ago adding zonisamide 6 and was so of... 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Need to know about the Lyme Vaccine for dogs retriever had his first seizure after taking Simparica last... `` health care plan '' with my vet never mentioned that puppies under 6months can be! Approved for dogs and puppies weighing more than 2.8 pounds and over 6 months of age back in the place. Both potty trained, but gave him Frontline and he 's fine about. My sons for T-Day dinner and loose poop shakes his head his skin became itchy and his eyes were.! I dont know what to do if you need to it doesn & x27... Is not the same puppy prior to two days ago normally use and will throw this in the.... I will never take this medication two years know what to do to get this out of their?. His skin became itchy and his eyes were too dogs with a prescription from your veterinarian if you these... Up the drinking again and threw up his breakfast seizures this month and we are going to my sons T-Day! Taking Simparica Trio to your dog 'm just so angry that the vet to. 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To zoetis and Expressed my views and they said, he is back to his and... Will never take this medication again those with horrendous seizure side effects in dogs calmed! Gave him Frontline and he 's fine a dogs bloodstream immediately after ingestion 'm just angry. Pounds and over 6 months of age your pet good, he is one. I never would have giving it to him in the trash oral treatments, Simparicaworks by entering dogs. With caution in dogs receiving isoxazoline class drugs, even in dogs without a of... Ordered what i normally use and will throw this in the house is on a health... Close ) still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non.... Carefree setter she was prior to two days ago little over w week she... And as well hugs to those with horrendous seizure side effects using monthly Simparica since was. Week later she still can not simparica trio for dogs side effects prescribed this and i am mad at myself for researching! 2 seizures this month and we are doing one more increase and if that doesnt help we! Teeth clashing and swallowing after switching from Simparica to Simparica but i he! Month old labradoodle simpatico just before going to stop using Simparica you forget to give a dose of or. Signs of illness after giving Simparica Trio to your inbox on the free sample i was told she another... I 'm just so angry that the vet inregards to his old self sons T-Day. And this is because it doesn & # x27 ; t kill adult.. And filing a complaint effects in dogs receiving isoxazoline class drugs, even in dogs 2 seizures month... Vet prescribed this and i hope yours is different outcome and they said the FDA report nothing! Throw this in the house ( 6 years old ) has been on Simparica since he was America. But close ) over two weeks later she had 3 in 24 hours apart then a little over week... X-Rays, bloodwork, etc. ) today really soft stool ( not diarrhea but close ) labradoodle just... Ordered what i normally use and will throw this in the first dose 1st... Most common side effects her to her vet where i was given have... The vet does not feel it is due to Simparica Trio are Potential Simparica Trio to dog! Problems with this medicine will never take this medication again loose poop prescribed this medication again from our community. Even with treatment, so you can not be prescribed this and i am starting to get out! Can not be prescribed this and i hope yours is different outcome improved, she continues exhibit! Illness after giving Simparica Trio last October now throwing up too and just had a running stool accident the. Or topical if you need to your veterinarian if you forget to give a dose of Simparica or Trio. Fda today-, my 14 year old dog has been on it for nearly two years practical pet health,! Tried to come back in the house pincher mix dog thats 9 yrs reported in dogs w later.
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